Transforming health care through teamwork


July 16, 2025


Natalie Caine poses for a picture in a sunlight lobby
Photo courtesy Mayo Clinic

When it comes to better patient care, it really does take a village to succeed.  

“When a team of experts works together to develop comprehensive, customized care plans, it leads to better outcomes for patients,” says Natalie Caine, MHA ’05, chief administrative officer at Mayo Clinic. “We’re the first and largest integrated group medical practice, which enables us to work on the most difficult to diagnose cases.” 

Mayo Clinic’s commitment to teamwork is evident in its dyad leadership model, where Caine provides administrative leadership and oversight alongside Amy W. Williams, MD, the executive dean of the practice. This multidisciplinary approach is present throughout the health system, ensuring that each physician is paired with an administrative leader. 

“As part of our leadership model, administrators rotate through different areas of the organization over time, allowing us to see how the different parts of Mayo Clinic work together,” Caine says. “I love being able to work with a team on challenging projects, where we have an opportunity to advance new innovation to support our patients and our staff, to ultimately bring more hope and healing.” 

During her 20-year career at Mayo, Caine has remained connected to Mizzou’s College of Health Sciences. She served on the college’s MHA alumni board, mentors health administration students and even works with several fellow Mizzou alumni at Mayo. 

“Mizzou has made a lasting impact on my life,” Caine says. “I’ve received so much from the MHA program and formed so many meaningful connections over the years.”